Looking for the best joint supplements to help protect your joints and improve your quality of life?

When most people think of supplements, they usually think of multivitamins or protein powder. Don’t get us wrong, these products can be great additions to your lifestyle and diet. 

However, people usually only start thinking of joint health supplements after it’s too late; when they’re already suffering from joint aches and pain. 

If that’s you and you’re researching the best joint supplements on the market, you’ve come to the right place. We’ve consulted nutritionists and physiotherapists to see what you should look for (in terms of ingredients) when making your decision. 

So, let’s get into which supplement we’ve chosen as the best choice to protect your joints. 

Best Joint Supplements 2021


Physio Flex Pro - Best Overall 

Physio Flex Pro is a cutting-edge joint supplement by SRS Nutra, an upcoming brand that’s gaining the right kind of attention (in fact, it’s getting pretty hard to avoid positive reviews!).

This joint health supplement ticked all of our boxes in terms of ingredients we were told to look for by physiotherapists and nutritionists. These included Glucosamine, Chondroitin Sulfate, MSM, Turmeric, and BioPerine.

Altogether, Physio Flex Pro contains 8 clinically proven ingredients overall that work in synergy, ensuring that customers get what they pay for with no costs being spared by SRS Nutra. 

It’s also personally recommended by physiotherapists around the world, including renowned Dr Kavita who specializes in orthopedics and musculoskeletal conditions - so you can be sure that Physio Flex Pro is the real deal. 


  • Proven to improve joint health - 8 clinically proven natural ingredients to improve mobility.  
  • Effective to reduce joint pain - experience heightened quality of life with less difficulty moving.
  • No risks of side effects - only contain clean ingredients that are clinically proven to be safe.
  • Made in the USA - manufactured in cGMP approved, FDA registered facilities.


Physio Flex Pro Ingredients: 

The formula of Physio Flex Pro is really what convinced us to try this joint supplement originally; it contains by far the best combination of ingredients we’ve seen on the market to promote joint health.

Not only that, with 8 quality ingredients in its formula, Physio Flex Pro contains the most ingredients out of the effective joint health supplements we rated on the market.

The 8 ingredients found in Physio Flex Pro are: 

  • Glucosamine: A naturally occurring amino acid that’s been proven to reduce joint pain and increase mobility in countless clinical studies. The top ingredient in joint supplements. 
  • Chondroitin Sulfate: Clinically proven to work in synergy with Glucosamine to maximize joint protection. 
  • Turmeric Extract: Contains high levels of the antioxidant curcuminoids that possess anti-inflammatory properties. Proven to reduce joint pain and increase east of movement. 
  • MSM (methylsulfonylmethane): Shown to be effective at increasing joint flexibility as well as being a potent anti-inflammatory agent, proven to decrease joint pain and improve mobility in clinical studies. 
  • Bromelain: A powerful anti-inflammatory enzyme found naturally in pineapples. Shown to repair and protect joint cartilage in studies as well as help with digestive comfort.
  • Ginger Extract: Another potent antioxidant with anti-inflammatory properties that’s known to ease joint pain. 
  • Bioperine: A patented form of black pepper extract that’s able to improve nutrient absorption, effectively improving the overall effectiveness of supplements it is included in.

Customer Reviews: 

We’re yet to see a negative online review of Physio Flex Pro. Customers state that it’s delivered on time and helped improve their quality of life by improving their ease of movement and reducing joint pain. 

Physio Flex Pro is even recommended by Dr. Kavita, a world-renowned doctor that specializes in Orthopedics and musculoskeletal conditions. 

ProJoint Plus 

The second place on our list is ProJoint Plus.  

In terms of a supplement containing great ingredients, this joint support supplement ticks the boxes for us; it contains turmeric, glucosamine, chondroitin and MSM. 

However, while it does contain great ingredients, it’s always important to look at the dosages too. ProJoint Plus contains slightly less MSM than we’d hoped for at 25 mg per serving (with our best option, Physio Flex Pro, offering 100 mg of MSM).


  • A great number of effective ingredients in its formula 
  • Positive reviews from customers 
  • Transparent supplement facts label 


  • Only 20 servings per container (less than 1 months supply)
  • Low dosage of key ingredients, such as MSM


The third place on our list is MoveMD by 1MD Nutrition. We liked that this supplement was also doctor recommended like our top joint supplement on this list, Physio Flex Pro. 

It contains 5 ingredients that are linked with improving your joints, but one of them is “Type X.I.V. Eggshell Membrane Collagen and Type II Chicken Collagen” - meaning this one isn’t for the vegans or vegetarians out there. 


  • Contains 5 ingredients linked with improving joint health 
  • Safe to use regularly
  • Budget-friendly
  • Free shipping on US orders


  • 5 ingredients doesn’t offer the most comprehensive package we’ve seen on the market
  • Not recommended to take on an empty stomach
  • Costs more if you don’t subscribe to monthly payments
  • You can only buy MoveMD from the manufacturer’s site


If you’re looking for a household name, then this is it - we’d be surprised if you haven’t already heard of this product. 

That being said, it’s not always the companies that advertise the most that end up being the highest quality; before we searched the market, we hadn’t seen most of the other products on this list, which have turned out to score higher. 

One thing we like about Arthrozene is that it contains Boswellia Serrata Extract, which has shown to be effective in the management of joint pain in numerous studies. 

We’ll end by pointing out that vegans and vegetarians shouldn’t take this as it contains collagen sourced from the chicken as well as “natural chicken comb extract”. 


  • Most well-known product on this list 
  • Contains Boswellia Serrata 


  • Not vegan friendly (contains collagen)
  • Most expensive on this list at $100 per months supply
  • Questionable customer reviews

 Relief Factor  

A popular joint supplement, Relief Factor makes it into our Top 5 joint health supplements on the market. 

It’s been on the market for quite a while gaining positive reviews (among some negative reviews). 

In terms of cost, Relief Factor offers a 3 week deal for less than $20 making it extremely budget-friendly - albeit, at the cost of losing a few week’s servings. However, this does force you to lock into a subscription too. 


  • The well known product that’s been on the market for a while 
  • The cheapest option on our list (if subscribing to monthly orders)
  • Good reviews from customers 


  • Locks customers into monthly subscriptions when they purchase their most cost-effective package
  • Not easy to find information about the ingredients in Relief Factor’s formula (lack of transparency)
  • You can only buy Relief Factor direct from the manufacturer’s site

What Are Joint Supplements and How Do They Work?

In general, joint supplements contain ingredients shown to help protect joint health and ultimately improve ease of movement. They are used by people from a wide range of lifestyles and age groups - from young athletes to office worker, to the older generation wanting to ensure optimal joint health. 

The effectiveness of each supplement is determined by the ingredients in their formula; if a product contains clinically proven ingredients, then it’ll be worthwhile, whereas if it only contains useless filler ingredients then it’ll be a waste of your cash (fortunately for you, we’ve conducted all the research and only recommended the best options available). 

What are the Benefits of Joint Supplements? 

This one is pretty self-explanatory. Joint supplements aim to provide benefits including; protecting your joints, reducing joint ache & pain, keeping your joints optimally lubricated, or help manage any other symptom of arthritis. 

In terms of the specific benefits of each product, it depends on which ingredients they contain in their formula. For example, Glucosamine offers a range of benefits including joint health support and reduced joint pain (and more), so you’ll experience these if the joint supplement you choose contains Glucosamine. 

Best Ingredients in Joint Supplements 

There are always 4 main ingredients that we always look for when choosing a joint supplement: Glucosamine, Chondroitin, Turmeric, and MSM. 

The above ingredients are the most clinically proven you can find at helping to support optimal joint health. 

Not only that, Glucosamine and Chondroitin are known to be more beneficial when ingested together in the same supplement in countless clinical studies.

By looking for specific ingredients on your search for the best joint supplement on the market, you’ll really see which companies have conducted the right research when formulating their product. For us, Physio Flex Pro is the top choice due to its containing 8 effective ingredients in its formula for a reasonable price. 

Can Joint Supplements Cause Side Effects? 

Before consuming any supplement, it’s a good idea to check whether it’s safe or not. 

The good news is that most natural joint health supplements on the market will contain safe ingredients. The ingredients we recommend such as Glucosamine and Chondroitin haven’t shown to cause any adverse effects in clinical studies and remain as generally very safe ingredients to consume. 

Always check whether the ingredients of a joint supplement are all-natural. If they’re completely natural, they’ll likely be safe from side effects. Whereas chemicals or drugs obtained from questionable sources may cause side effects - this is also why it’s important to ensure all supplements you purchase are made from cGMP certified and FDA registered facilities. 


Hopefully, our guide on the best joint supplements has highlighted the importance of making the right decision (and conducting enough research to do so). 

Luckily for you, we’ve done all the hard work and found the best options on the market to keep your joint health at an optimal level; we found that Physio Flex Pro offered clinically effective ingredients in a reasonably priced package (with discounts offered on multi-box deals). 

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About the Author

Steven has been into health, nutrition, and fitness for over 10 years, and has a degree in Physical Education and Coaching. He is an expert in supplements and is devoted to helping his clients achieve their fitness goals and live their best lives.

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